Mechanism of vacuole inheritance

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In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae

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During budding in Saccharomyces cerevisiae, maternal vacuole material is delivered into the growing daughter cell via tubular or vesicular structures. One of the late steps in vacuole inheritance is the fusion in the bud of vesicles derived from the maternal vacuole. This process has been reconstituted in vitro and requires isolated vacuoles, a physiological temperature, cytosolic factors, and ...

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Early in S phase, the vacuole (lysosome) of Saccharomyces cerevisiae projects a stream of vesicles and membranous tubules into the bud where they fuse and establish the daughter vacuole. This inheritance reaction can be studied in vitro with isolated vacuoles. Rapid and efficient homotypic fusion between saltwashed vacuoles requires the addition of only two purified soluble proteins, Sec18p (NS...

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ژورنال

عنوان ژورنال: PLANT MORPHOLOGY

سال: 2012

ISSN: 0918-9726,1884-4154

DOI: 10.5685/plmorphol.24.105